Imatinib-Induced Erythema Nodosum : A Case Report and Literature Review
Journal Title: Journal of Dermatology Research and Therapy - Year 2016, Vol 2, Issue 4
Abstract
The list of drugs inducing an erythema nodosum is long and is extending. Their accountability is difficult to ascertain; rare observations relate positive drug provocation tests. Observation: We report a case of subintrant push of erythema nodosum caused by the Imatinib (Glivec) administration in a patient aged of 34 years old and followed for chronic myeloid leukemia. The drug provocation test was positive. In front of the recurrent, the painful character, the significant functional deficiency caused by the lesions and the positive drug provocation test, the imatinib was finally stopped. The evolution was characterized by the absence of recurrence 2 years after stopping the treatment. Conclusion: Even if it is exceptional, the Imatinib may induce severe erythema nodosum imposing its stopping. Such side effects should be reported to improve their monitoring and treatment.
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- EP ID EP344207
- DOI 10.23937/2469-5750/1510030
- Views 122
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