Immunoglobulin G4 deficiency can be a new entity for primary recurrent miscarriage: Successful pregnancy in two cases after treatment with intravenous immunoglobulin
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2019, Vol 16, Issue 4
Abstract
Recurrent miscarriage is one of the complications of pregnancy in which the potential role of immunologic factors has already been mentioned. Here, two young women with recurrent miscarriage were consulted in the infertility center. The diagnosis of immunoglobulin G4 (IgG4) deficiency was made through the reduction of IgG4 Ig levels and normal total IgG titer. Considering this abnormality, intravenous Ig 200 mg/kg was started monthly, and they both had successful pregnancies. Little is known about IgG4 deficiency in women with recurrent miscarriage. IgG4 deficiency should be taken into account in these patients. It is expected that these results will shed further light on the feasibility of intravenous Ig for women with recurrent miscarriage.
Authors and Affiliations
Behzad Shakerian, Mozhgan Moghtaderi, Nasrin Heidari
Keywords
Related Articles
- EP ID EP684638
- DOI 10.4274/tjod.galenos.2019.02650
- Views 175
- Downloads 0
Spinal versus general anesthesia in gynecologic laparoscopy: A prospective, randomized study
Objective: To compare spinal anesthesia (SA) with general anesthesia (GA) in gynecologic laparoscopic surgery regarding anesthetic parameters and patient satisfaction together with an assessment of total oxidant, antioxi...
Uterine giant cell carcinoma: a case report and review of the literature
Endometrial carcinoma is the most common genital malignancy in women. Endometrioid type is the most common variant of endometrial carcinoma described in literature. Giant cell carcinoma is a rare, and infrequently report...
Searching for radiologic and histologic evidence on live vaginal tissue: Does the G-spot exist?
Objective: There is a growing debate on the existence of the G-spot. G-spot amplification by various surgical interventions has become mainstream for esthetic vaginal surgery despite a lack of conclusive proof of the G-s...
Utility of the “floating ball sign” in diagnosis of ovarian cystic teratoma
Objective: To evaluate the incidence of the “floating ball” sign in cross-sectional imaging modalities in patients with ovarian teratoma, and to investigate the relationship between the morphologic features of the terato...
Repeated dose of prostaglandin E2 vaginal insert when the first dose fails
Objective: To compare the obstetric and neonatal outcomes of patients treated with repeated-dose prostaglandin E2 (dinoprostone) vaginal insert when the first dose fails. Materials and Methods: This retrospective study...