Immunomodulatory Аspects and Mechanisms of Аction of βGlucans
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2017, Vol 1, Issue 6
Abstract
β-glucans are found in bacterial and fungal cell walls and have been implicated in the initiation of anti-microbial immune response. β-glucansact on Dectin-1, complement receptor (CR3) and TLR-2/6 immune receptors. They trigger a group of immune cells including macrophages, neutrophils, monocytes, natural killer cells and dendritic cells. Most β-glucansenter the proximal small intestine and some are captured by the macrophages. They are internalized and fragmented within the cells, then transported by the macrophages to the marrow and endothelial reticular system. The small β-glucans fragments are eventually released by the macrophages and taken up by other immune cells leading to various immune responses.
Authors and Affiliations
Voycheva C*
Keywords
Related Articles
- EP ID EP745871
- DOI 10.23880/oajpr-16000132
- Views 19
- Downloads 0
The LC-MS and GC-MS Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Silver Sulfadiazine
Silver sulfadiazine is a topical antibiotic helps to prevent and treat wound infections in patients with severe burns. This research was performed to evaluate the impact of the Trivedi Effect®- Consciousness Energy Heal...
The Utilization of Residue Come Out as a By-Product by the Cold Press
In recent years, with the increase of the world population, the studies on the utilization of the herbal wastes resulting from increased industrialization and production have gained speed and importance. Vegetable oils t...
A Brief Review on Different Chromatographic Techniques
Chromatography is a separation process used to separate components in a mixture. The components of the mixture are dispersed in a liquid solution known as the mobile phase, which holds it through a structure containing...
β-Carbonic Anhydrase as a Target for Eradication of Mycobacterium tuberculosis
Infectious diseases are among the most danger, and deadly afflictions that human societies suffering from there. One of the common re-emerged infectious diseases is tuberculosis (TB). The causative pathogen for this dise...
Evaluation of the Effect of Consciousness Energy Healing Treatment on Physicochemical and Thermal Properties of Flutamide
Flutamide is used primarily to treat the prostate cancer, which blocks the action of exogenous testosterone by binding to the androgen receptor. The aim of this study was to evaluate the impact of the Trivedi Effect®-Con...