Immunomorphological aspects of thymus structure in the case of children of the first year having inherent valvular diseases
Journal Title: Медицинский альманах - Year 2016, Vol 2, Issue 2
Abstract
Thymuses investigated biopsies from children 1 year of age (n = 77) in patients with congenital heart defects of varying difficulty. Immunohistochemistry verified the accumulation of keratin in epitelioretkulotsitah (PanCK), thymopoiesis assessed by expression of CD3+. Serum levels thymuline investigated. The degree of complexity of heart disease determines the morphological changes in the body, under which a large complex tissue reactions. During the first year of life (1, 6, 11 months.) In the thymus was observed decrease in the expression of keratins, accompanied by a breach of the architectonics of epithelial stroma, which affect the level of thymopoiesis, lowering it. Studies have shown that immunomorfologicheskie features correlated with the degree of complexity of a heart defect and the level of hormones in the peripheral blood, which was significantly lower than in healthy children.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP215378
- DOI 10.21145/2499-9954-2016-2-98-101
- Views 98
- Downloads 0
Study of experience of famous doctors as factor of medical specialists training
The article discusses the question of study historically famous doctors` memoirs in the course of medical education. It is new way to improve quality of medical education. Conditions and results of the survey, made by th...
Results of comprehensive treatment of the patients having chronic recurrent central serous chorioretinopathy
Purpose: assessment of efficacy of step-by-step complex treatment of patients with chronic relapsing central serous horioretinopathy using method of focal laser coagulation and subthreshold microimpulse laser influence....
Comparative characteristics of morbidity rate, mortality and expected life duration of men and women in the Crimea
In article analyzed the health outcomes, mortality and life expectancy of men and women in a comparative perspective in the Republic of Crimea in 2008-2013y. It was revealed that man sought medical help for diseases much...
Immunomorphological aspects of thymus structure in the case of children of the first year having inherent valvular diseases
Thymuses investigated biopsies from children 1 year of age (n = 77) in patients with congenital heart defects of varying difficulty. Immunohistochemistry verified the accumulation of keratin in epitelioretkulotsitah (Pan...
Immunodiagnosis of tumors
his review article represents the information about immunodiagnostics of tumor using oncomarker aimed to assess the efficiency of therapy, to reveal residual and recurrent tumors, to diagnose and to predict neoplastic pr...