Impact of different modifiable factors on hearing function in type 1 and type 2 diabetic subjects . A preliminary study
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2013, Vol 20, Issue 4
Abstract
Introduction and objective: Hearing impairment in diabetic subjects is more prevalent than in the general population. Ageing, noise exposure and smoking are known as risk factors of hearing loss. The aim of this study was to assess whether other factors, such as HbA[sub]1c[/sub], blood pressure, serum lipids and BMI have an impact on hearing function among relatively young diabetic subjects. Materials and Methods: 58 patients, 31 with type 1 diabetes and 27 with type 2 diabetes, aged < 45 years, with diabetes duration < 10 years and without overt hearing impairment were included. In all subjects, vital signs, laboratory tests, pure-tone audiometry and trancient-evoked otoacoustic emissions (TEOAE) were evaluated. Results: Hearing impairment was revealed in 20 subjects. This group had a lower HDL-cholesterol level compared with normal hearing patients (44.2 mg/dl vs. 57.6 mg/dl, p=0.007). Absence of otoacoustic emissions was diagnosed in 16 subjects. These patients also had a lower HDL-cholesterol level compared with subjects with TEOAE present (45.4 mg/dl vs. 55.2 mg/dl, p=0.018). Hearing threshold was inversely correlated with HDL-cholesterol level, and positively correlated with triglycerides. Patients with HDL-cholesterol level ≥50 mg/dl had lower hearing threshold at frequencies 0.5–12 kHz, as well as higher TEOAE amplitude. Subjects with triglycerides above median had a higher hearing threshold at frequencies 0.5–12 kHz, as well as lower TEOAE amplitude. Patients with elevated BMI (≥25 kg/m[sup]2[/sup]) had a higher hearing threshold at frequencies 2–12 kHz, as well as lower TEOAE amplitude. Conclusions: Hearing impairment is frequent among relatively young diabetic subjects. The preseted study reveals that factors like HDL-cholesterol, triglycerides, and BMI may affect hearing function in this group.
Authors and Affiliations
Mariusz Dąbrowski, Grażyna Mielnik-Niedzielska, Andrzej Nowakowski
Keywords
Related Articles
- EP ID EP80703
- DOI -
- Views 110
- Downloads 0
Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions
Depression is becoming a growing problem in rural areas. This psychiatric disorder often accompanies epilepsy. The aim of this study was to assess the influence of fluoxetine (FXT), a commonly used antidepressant, on the...
Studies and measurements of physical activity of the society
Physical activity, as a very important factor conditioning ontogenesis and state of health, is the key element of a health promoting life style. Physically able individuals manifest a considerably higher motivation for w...
Epidemiology of animal bites and other potential rabies exposures and anti-rabies vaccine utilization in a rural area in Southern Ethiopia
The presented report describes the epidemiology of potential rabies exposures and examines the utilization of anti-rabies vaccine in a rural area of Ethiopia during a period of 43 months. A total of 683 persons (51.1% fe...
[i]In vitro [/i]evaluation of cytotoxicity of n-hexane extract from [i]Alnus sieboldiana[/i] male flowers on VERO and HEK293 cell lines
Introduction and objective. Alnus sieboldiana (Betulaceae) is a warm temperate tree distributed in highland areas along the Pacific shores of central Japan. The aim of the study was to evaluate the cytotoxic activity of...
Cardiohepatic interactions – cirrhotic cardiomyopathy and cardiac cirrhosis
Interactions between the heart and the liver have been under investigation for many years. Cirrhotic cardiomyopathy characterized by hyperdynamic and hyporeactive circulation has been described in patients with advanced...