IMPLEMENTATION OF PI-RADS IN PROSTATE CANCER WITH 3 TESLA MRI- A PILOT STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 14
Abstract
BACKGROUND For standardising of multiparametric magnetic resonance (MR) imaging of the prostate, the European Society of Urogenital Radiology published Prostate Imaging Reporting and Data System (PI-RADS) in 2012.1,2 Later it was validated and the PI-RADS sum score for summation of the single score for the three different pulse sequences (T2-weighted imaging, diffusion-weighted imaging [DWI] and dynamic contrast material-enhanced [DCE] was being used. MRI has an emerging role in facilitating the diagnosis of prostatic malignancy. The purpose of the present study was to correlate the results of TRUS-guided targeted prostate biopsy with the PI-RADS scoring (Version 2) on MP-MRI in patients, wherein prostatic malignancy has been suspected. MATERIALS AND METHODS This was a descriptive study done at Yenepoya Medical College, Deralakatte, Mangalore over a period of 6 months after obtaining ethical clearance. 30 patients were included in the study. Inclusion Criteria being- Patients with PSA > 4 ng/dL. Patients with palpable lesion on digital rectal examination. The data so obtained was tabulated in Excel Sheet and analysed for sensitivity, specificity and other statistical tests for individual parameters. RESULTS 30 patients underwent MRI and TRUS-guided biopsy. Mean age of patients was 64 years, ranging from 52 - 79 years. All these patients had increased PSA levels. All these patients who underwent MP-MRI had a documented PI-RAD score. 4 of them had PIRAD I, 5 of them had PI-RAD III, 9 of them had PI-RAD IV and 12 of them had PI-RAD V. 21 patients with PI-RAD IV and PI-RAD V on imaging showed positive for malignancy on HPE showing significant association on Chi-square test with x2= 18.122 and p= < 0.001 (statistically significant). CONCLUSION In our study, we found that a very good correlation with positivity of prostate cancer on HPE with higher PI-RADS (IV and V). PIRAD overall score was sensitivity (90%) compared to its component alone (DWI- 69%, T2- hypointensity- 68%). This was similar to previous observation done by Junker et al. PI-RAD scoring is better done on 3 Tesla than 1.5 Tesla.
Authors and Affiliations
Adarsh K. M, Muhammed Shahab M. K, Pavithra H, Devadas Acharya, Ravichandra G, Vinayaka U. S
Keywords
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- EP ID EP414368
- DOI 10.14260/jemds/2018/408
- Views 75
- Downloads 0
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