Importance of lipid-lipoprotein ratios as a diagnostic tool in metabolic syndrome population
Journal Title: National Journal of Physiology, Pharmacy and Pharmacology - Year 2018, Vol 8, Issue 12
Abstract
Background: Metabolic syndrome (MS) is a constellation of diseases caused by several interconnected cardiometabolic risk factors such as obesity, hypertension, hyperglycemia, and dyslipidemia. Lipid-lipoprotein ratios can be considered as an alternative for identifying individuals with MS. Objectives: The objectives of this study were to compare the lipid profile and lipid-lipoprotein ratios of different groups formed based on the progression of the severity of MS. Materials and Methods: A total of 195 participants who volunteered with the signs of MS were divided into three groups based on the presence of metabolic abnormalities as Group I (with <3 components of MS - control group), Group II (with any three components of MS group), and Group III (with >3 components of MS - severe MS group). Results: Results showed that triglycerides (TG), ratio of TG-to-high-density lipoprotein, and total cholesterol (TC)-to-high-density lipoprotein ratio showed significant difference (P < 0.001) between the groups, whereas the results of high-density lipoprotein and lowdensity lipoprotein-to-high-density lipoprotein ratio were significantly more (P < 0.001) in severe MS in comparison with control and MS. TC showed significant difference (P = 0.004) in MS and severe MS when compared with that of control. Conclusion: Early identification and treatment of individuals with MS is very important to prevent debilitating effects associated with its development.
Authors and Affiliations
Bhagyashree N, Ganesh M, Ramaswamy C
Keywords
Related Articles
- EP ID EP497921
- DOI 10.5455/njppp.2018.8.1031216102018
- Views 76
- Downloads 0
Investigating guided imagery on depression in patients with Type 2 diabetes
Background: Diabetes is one of the major health problems and one of the most prevalent metabolic chronic diseases and its resulting complications are one of the main mortality factors in the world. Prevalence of depressi...
Perception of vibration threshold is a marker of diabetic neuropathy
Background: Diabetes mellitus is a chronic progressive disorder and is concerned because of its devastating complications. Among this, nervous system is most frequently affected. Symptom varies widely in peripheral neuro...
Risk factors for pneumonia in acute stroke patients admitted to the Emergency Department of a Tertiary Government Hospital
Background: Knowledge on the risk factors of developing pneumonia, one of the top causes of mortality in acute stroke patients admitted to a tertiary government hospital, is lacking. Aim and Objective: This study aimed t...
Impact of distant and regional metastasis of non-small-cell lung cancer on endotoxicosis development
Background: The complex metabolic disorders and non-specific clinical manifestations that accompany the development of malignant neoplasm are characterized as a syndrome of endogenous intoxication. Aims and Objectives: T...
Biochemical assessment of the hepatic functions of the petrol pump workers of Jaipur city
Background: In recent years, occupational health hazards have grown as one of the major public health issues worldwide. In this context, petrol pump workers were studied who by virtue of their occupation is continuously...