Importance of piperidone moiety in pharmaceutical chemistry: a review
Journal Title: Journal of Applied Pharmaceutical Research - Year 2015, Vol 3, Issue 2
Abstract
Piperidone heterocycle have gained a considerable attention in the field of drug discovery. The wide range of its therapeutic application paved the way to the researchers to insert the nucleus every now and then in diversified pharmacophore, so as to generate novel therapeutic profile. In this review, we have tried to present various therapeutic applications, which have already been demystified by the researchers. The study may prompt the researcher to generate scaffolds of highest therapeutic efficacy considering the importance of 4- Piperidone nucleus
Authors and Affiliations
Sourav De, Suhasis Banerjee, M. Niranjan Babu, C. Navaya Keerithi
Pharmacognostic Evaluation and Physico-chemical Analysis of Ulmus wallichiana Planch.
The plant Ulmus wallichiana Planch. (Family: Ulmaceae) is found in Himalayan regions from Afghanistan to West Nepal. In India, it is found in Kumaun and Garhwal hills of Uttarakhand (India), locally known as Chamarmou. B...
Formulation and characterization of organic- inorganic hybrid film for transdermal drug delivery
A novel organic inorganic hybrid film-forming gel for transdermal application was developed by poly vinyl alcohol using Di methyl polysiloxane as an inorganic-modifying agent, poly N-vinyl pyrrolidone as a tackifier and...
Clock gene variation in type 2 diabetes: a review
Diabetes mellitus type 2 is a long-standing metabolic disorder that is exemplify by high blood sugar, insulin resistance, and comparative lack of insulin. General symptoms include increased thirst, frequent urination, an...
Recent advancement in daignosis of gastrointestinal diseases
Gastrointestinal diseases refer to ulcerative disorders of the upper gastrointestinal tract. Stomach acids and some enzymes can damage the lining of the G.I. tract if natural protective factors are not functioning normal...
Inspection of a novel penetration enhancer for transungual drug delivery system: Pelargonium hortorum
This study was to search some natural penetration enhancer and formulate them in a transungual drug delivery formulation. This natural penetration enhancer helps to overcome the main problem in front of success of trans...