Improved Thermal Ablation of Tumors Using A Real-Time Local Data Measurement System
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2018, Vol 11, Issue 5
Abstract
An innovative approach based on the biochip technology for real-time monitoring of a thermal therapy applied in oncology is proposed in this paper. The proposed system provides two primary functions: real-time tracking of the targeted tissue’s thermal diffusion while at the same time locally characterizes and provides the parameters of the tissue. To validate our new approach, we use the Finite Difference Method (FDM) to solve the problem numerically and accurately predict the variation of the temperature. Numerical simulation results confirmed the efficiency of such an approach. Moreover, a hardware implementation of the discretized Bio Heat Transfer (BHT) Model using a Field Programmable Gate Array (FPGA) board was successfully achieved. The hardware implementation demonstrates that the proposed system can predict the future variation of the temperature readings and locally characterizes the tissue, allowing the user to adjust safely to subsequent injection doses. This new system shows promise in improving the efficiency of thermal therapy in oncological practice.Thermal therapy has been approved as an effective treatment for many diseases, especially in cancerous tumors [1,2]. This therapy was born a long time ago, and it has been improved and entertained for decades. Nowadays, different techniques involving thermal therapy principles are available. We can categorize these techniques into diverse groups following the nature of the injected energy and the modality of administration. It contains among others the sources using Electromagnetic (EM), Ultra Sound (US) and Radio Frequency (RF). Thermal therapy, known commonly as thermotherapy, uses heating sources as well as cooling sources [2]. Real-time monitoring of a thermal therapy used for cancer treatment can improve the efficiency of the treatment and reduce damage to healthy tissue surrounding the targeted tumor. For this reason, different systems based mostly on image processing and sensors network, are used nowadays.Although a significant development was accomplished in the technological devices and numerical methods, the thermal therapy still suffers from a lack of precision and high accuracy. Significant collateral damage will, indeed, occur during the thermal treatment procedure. This collateral damage could be fatal for the patient. For this reason, a new technique has been developed to control the injected power for the purpose to minimize the risk of overheating the healthy surrounding tissue. This technique is known as dosimetry which is associated with an imaging system as Magnetic Resonance Image (MRI) for monitoring the delivered power. This novel approach, MRI-guided thermal therapy, has been widely deployed in the last decades [3,4].
Authors and Affiliations
Idir Mellal, Youcef Fouzar, Aziz Oukaira, Emmanuel Kengne, Ahmed Laklissassi
Keywords
Related Articles
- EP ID EP592711
- DOI 10.26717/BJSTR.2018.11.002156
- Views 155
- Downloads 0
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