IMPROVEMENT OF PREVENTION RADIATION REACTIONS AS WELL AS PREVENTION OF LATE COMPLICATIONS OF CHEMORADIOTHERAPY FOR CERVICAL CANCER
Journal Title: Наукові праці. Серія "Техногенна безпека" - Year 2016, Vol 280, Issue 268
Abstract
Dynamic monitoring, medicamental prevention and timely correction of treatment programs helps to ensure that the conduct of chemoradiotherapy to patients with locally advanced cervical cancer does not increase the toxicity of radiation reactions and the appearance of complications from critical organs and tissues. Chemoradiotherapy has been done to 298 patients with locally advanced cervical cancer IIB – IIIB tumor stage (T2b-3bN0-1M0) by developed methods of the complex conservative therapy. These methods are based on individual planning of radiotherapy on the criterion of not exceeding the level of tolerance for a normal tissues. Also there were evaluated the severities of general and local chemoradiation reactions from the «critical» organs and systems. The datas which represented in the article are indicating: the usage of radiomodifying doses of cytostatic medicaments during combined radiotherapy technologies that has been developed by us, do led to increasing of the number and severity of toxic effects just till 2nd level, but not over that value. Local application of hyaluronic acid, is safe and effective therapy to prevent and treat of the radiation-induced cystitis. Reduction of early radiation reactions as well as prevention of late complications are done by using of modern topometric training technologies, personal computer planning and correct implementation of the planned combining radiotherapy course.
Authors and Affiliations
V. Ivankova, T. Nesterenko, L. Baranovska
Keywords
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