In vitro antibacterial analysis of copper solution (microparticle) – a novel anti-infective molecule for wound management
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Now a days the emergence of antibiotic resistant bacterial pathogens are considered as the major alarm, there is a need to concentrate on the synthesis of new antibacterial agents. Most of the public getting aware about the beneficial role of conventional methods like usage of copper and silver vessels to act against bacterial pathogens. Copper is a trace element metal particle that is highly useful to inhibit microbial growth in media by means of disrupting membrane permeability leads to cellular damage and cytolysis. To keep all these in mind an objective with the study of in vitro antibacterial analysis of copper in solution to bacterial pathogens isolated from the wounds. Battery of seven bacterial isolates for wound and six laboratory bacterial strains were included in this investigation. As a result, among the wound isolates, Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa inhibited at the maximum concentration of 4% copper solution with 20mm zone of inhibition each; whereas among laboratory isolates Serratia sp and Providencia rettigeri were shown with 20 and 18mm inhibition. Thus from this study, it was clearly identified that the copper may be useful as external antibactieral solution for wound care and avoiding infections.
Authors and Affiliations
Pramila M, Meenakshisundaram M, Prabhusaran N, Lalithambigai R, Karthik P
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