IN-VITRO ANTIBACTERIAL EFFICACY OF SOLVENT EXTRACTS OF LEAVES OF BAUHINIA RACEMOSA LAM. (CAESALPINIACEAE) AGAINST ENTERIC BACTERIAL PATHOGENS
Journal Title: International Journal of Pharmaceutical Sciences and Drug Research - Year 2011, Vol 3, Issue 1
Abstract
Phytochemical screening of the plant leaves reveals the presence of carbohydrates, alkaloids, flavonoids, steroids, and tannins. Petroleum ether extract, chloroform extract, ethyl acetate extract and methanol extracts of leaves of Bauhinia racemosa Linn. were prepared and antibacterial activity were studied by disc diffusion method against certain enteric bacterial pathogens such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aerogenes, Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella typhi, Staphylococcus epidermidis and Proteus vulgaris. The Methanol extracts had wide range of antibacterial activity against enteric bacterial pathogens than the petroleum ether extract, where as ethyl acetate extract were slightly higher antibacterial activity than chloroform extract. Antibacterial activity of various extract of leaves of Bauhinia racemosa was carried in attempt to develop a new pharmaceutical drug from natural origin for prevention of enteric infection.
Authors and Affiliations
S. B. Dahikar, S. A. Bhutada, D. H. Tambekar, S. K. Vibhute
Keywords
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