In Vitro AntiDiabetic Activity of Costus igneus roots
Journal Title: PARIPEX-Indian Journal of Research - Year 2017, Vol 6, Issue 8
Abstract
Objective: In vitro analysis of the anti-diabetic effect of various extracts of the medicinal plant Costus igneus roots. Methods: Extracts of the plants were prepared by cold percolation. They were then tested for inhibition of α-amylase activity and α-glucosidase activity. Results: Inhibition of amylase and glucosidase enzymes involved in digestion of carbohydrates can significantly decrease the post prandial increase of blood glucose after a mixed carbohydrate diet and therefore can be an important strategy in management of blood glucose. The hydroethanol extract of Costus igneus roots showed strong inhibition of α-amylase and α-glucosidase. Conclusions: The findings indicate that all the extract of the plant possess antidiabetic properties too varying degrees. They can be used to develop natural drugs which may be used in lieu of commonly used strong allopathic drugs which possess a number of harmful side effects.
Authors and Affiliations
DR. SELVARAJ . R, DR. THAMIZHARA SAN. S, DR. UMAMAHESW ARI. S
Keywords
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