IN VITRO ANTIMALARIAL ACTIVITY OF THAI PICRASMA JAVANICA Bl STEM EXTRACT
Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2016, Vol 5, Issue 4
Abstract
The in vitro antimalarial activity against Plasmodium falciparum K1 of the four extracts from the stem of Picrasma javanica Bl, that is, water, methanol, chloroform and hexane were studied using a modification of the [3H]hypoxanthine incorporation method. It was found the chloroform and hexane extracts showed in vitro antimalarial activity with IC50 of 21.6 g/ml and 33.2 21.6 g/ml, respectively. While, the methanol and water extracts were inactive against parasite. In addition, the methanol extract of leave showed the activity against P. falciparum K1 with IC50 of 21.7 g/mL. Chemical constituent investigations of stem and leave of this medicinal plant may bring to the new lead structures for developing new antimalarial drugs.
Authors and Affiliations
Chalerm Saiin
Keywords
Related Articles
- EP ID EP204481
- DOI -
- Views 117
- Downloads 0
Innovative Importance of Research of Traditional Handicraft Wares of Ganja on the Basis of Biochemical Methods
For the first time has been researched the significance of traditional craftsmanship patterns from ethnographic and archaeological point of view in investigation of development of features of urban culture in Ganja on th...
CEMENT 222RN AND 226RA CONCENTRATION MEASUREMENTS IN SELECTED SAMPLES FROM DIFFERENT COMPANIES
Solid-state nuclear track detectors (CR-39) are widely used for radon exhalation rate measurements in cement under different conditions. The detectors were exposed to standard radon concentration from a standa...
AN APPRAISAL OF ENVIRONMENTAL HEALTH & SAFETY MANAGEMENT IN THE WORKPLACE (A STUDY OF CONTINENTAL SHIPYARD LIMITED)
There is need to ensure that in everything we do the safety of human life is given the utmost priority. Human life is priceless and the strongest desire of every normal person is to stay healthy and...
THE QUALITY OF HOME HEALTHCARE SERVICE IN RIYADH/SAUDI ARABIA
Background: Home healthcare services are expanding in Saudi Arabia at a rapid pace in order to meet the need of growing population of older adult and those with chronic illnesses and the quality of this service is variou...
MORINDA JUICE (MORINDA CITROFILIA L) TO PURIFY THE WASTED COOKING OILS
Purifying the recycling wasted vegetable cooking oil sometimes is needed. This research used the Morinda Citrofilial (Morinda Juice) as medium to purify the wasted cooking oil. It was designed to investigate whether Mori...