IN VITRO ASSAYS TO INVESTIGATE THE ANTI-INFLAMMATORY ACTIVITY OF HERBAL EXTRACTS: A REVIEW
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12
Abstract
The article reviews recent studies on the anti-inflammatory effects of herbal extracts with emphasis on different assays that are frequently used to test the in-vitro anti-inflammatory activity of herbal constituents. Protein denaturation assays and membrane stabilization assays are frequently used to evaluate in vitro anti- inflammatory activities. Many researchers have used minimum of three in vitro assays to evaluate anti- inflammatory activity of herbal constituents. Diclofenac, acetyl salicylic acid and indomethacin are the drugs used as reference standard more frequently. We suggest to reduce the use of animals in conducting anti-inflammatory activity in vitro studies as animal ethics is important as human welfare.
Authors and Affiliations
Jayasuriya W. J. A. B. N.
Keywords
Related Articles
- EP ID EP674697
- DOI -
- Views 171
- Downloads 0
HOUSEHOLD REMEDIES IN SCORPION ENVENOMATION
Scorpion stings are common emergency events in many parts of the world. It is a major public health problem in many underdeveloped tropical countries, especially in rural parts of India. Scorpion envenomation is an occup...
DIET AND LIFESTYLE IN THE PREVENTION OF OVULATORY DISORDER INFERTILITY
Diet, exercise, and energy expenditure (physical activity) define the ―energy balance‖ which modulates body habitus. These modifiable lifestyle factors provide an opportunity for therapeutic intervention in the subfertil...
PHYTOCHEMICAL AND ANTIBACTERIAL OF MORINGA OLEIFERA LEAVES
Background and Objective: The aim of this study was the determine in vitro antibacterial activity of different extracts of Moringa oleifera leaves against clinical isolates and standard bacteria, determine the Minimum In...
LUTEINIZING HORMONE AND FOLLICULAR STIMULATING HORMONE LEVELS AFTER SUCCESSFUL KIDNEY TRANSPLANTATION IN SUDANESE MALE
Male patients with chronic kidney disease often exhibit the biological and clinical hallmarks of an abnormal hypothalamus–pituitary–gonadal axis. It is known that dialysis does not reverse this impaired endocrine status,...
THE HEPATOPROTECTIVE IMPACT OF MORINGA OLEIFERA LEAVES EXTRACT AGAINST SODIUM VALPROATE- INDUCED LIVER TOXICITY IN ADULT RATS
Objective: Valproic acid and its salts (sodium valproate, VPA) are mood stabilizing and anticonvulsant agents. VPA use has been complicated by a high incidence of hepatic injury. Moringa oleifera (MO) leaves extract exhi...