In Vitro Degradation and In Vivo Skin sensitisation study of Hernia Mesh - Sterilized Partially Absorbable Tissue Separating Dual Layered Surgical Mesh
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2022, Vol 2, Issue 09
Abstract
As hernia mesh implants are used to reinforce the abdominal wall, several complications can occur, such as hernia recurrence, abdominal pain, seroma formation and infection, depending on their biocompatibility. The polymer coated knitted mesh is used to repair hernias by providing a flexible scaffold. Theobjective of this study was to assess skin sensitisation potential of polar and non-polar extract and In Vitrodegradation andIn Vivo skin sensitisation pattern for polymer coated knitted mesh. The guinea pig maximization test (GPMT) is usually performedwith one moderately irritant induction dose of the allergen and gives a qualitative assessment hazard identification of the allergenicity of the chemical. The apparent morphological change, weight, and strength loss rate of the mesh all showed the degrading impact. The degradation of polymer coated knitted mesh is performed to check polymer layer pattern after implantation
Authors and Affiliations
Minocha Dr. Pramod Kumar, Kothwala Deveshkumar Mahendralal, Durani Mohamadovesh Mohamadyasin, Shaikh Aamir Sohel Mukhtar
Keywords
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- EP ID EP733563
- DOI 10.47191/ijmscrs/v2-i9-06
- Views 28
- Downloads 0
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