IN-VITRO PHARMACOLOGICAL INVESTIGATIONS OF THE PLANT BOERHAVIA REPENS (FAMILY: NYCTAGINACEAE)
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 7
Abstract
Boerhavia repens is an important medicinal plant having application in jaundice, fever and various other disorders. The whole plant Boerhavia repens was sun dried and extracted using methanol. Later the crude methanolic extract was fractionated into four different fractions using Petroleum ether, carbon tetra-chloride, Di-chloromethane and Ethyl acetate. The anti-oxidant activity of the different fractions was measured by the DPPH free radical scavenging activity. The ethyl acetate and the di-chloro methane soluble fractions showed very potent anti-oxidant activity by the DPPH free radical scavenging method. The anti-microbial activity of the different fractions was measured by disc diffusion method. The antimicrobial screening of the plant showed that the carbon tetra-chloride soluble fractions and the Petroleum ether soluble fractions showed mild antimicrobial activity. Evaluation of cyto-toxic activity was done using the brine-shrimp lethality bio-assay. The petroleum ether soluble fraction and the ethyl acetate soluble fractions showed significant cyto-toxic activity.
Authors and Affiliations
Avijit Dey, S. M. Rahman, Rezwana Chowdhury, Md. Hamiduzzaman, Mohammad Alvi
Keywords
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