Incidence, etiological risk factors and outcome of glucose-6 phosphate dehydrogenase deficiency (G6PDD) among neonates presenting with hyperbilirubinemia in tertiary care hospital, Punjab.
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2017, Vol 3, Issue 3
Abstract
Objectives: The aim of this study was to analyse the incidence and outcome of G6PD deficiency(G6PDD) among neonates presenting with hyperbilirubinemia and to evaluate other etiological risk factors associated with hyperbilirubinemia. Methods: This was a prospective study conducted on jaundiced neonates, over a period of 6 months. Perinatal history was taken. Laboratory parameters included serum bilirubin, haemoglobin, peripheral blood film and blood groups. Treatment modality and outcome was noted during the hospital stay. Results: The incidence of G6PDD was found to be 4.16% and only in males. Total serum bilirubin level in G6PD deficient cases was (mean =22.72±5.1), which is significantly higher when compared with other causes of jaundice(Physiological, Cephalhematoma, Idiopathic) except ABO and Rh incompatability. Physiological jaundice was the most common cause of neonatal jaundice (45.83%). Conclusions: G6PDD is one of the common causes of most severe form of neonatal jaundice with higher hemoglobin levels and significant hyperbilirubinemia predominantly in males and can present with jaundice earlier than other etiologies . Babies with G6PDD can present earlier and can have serious consequences.
Authors and Affiliations
Karnail Singh, Palwinder Singh , Munish Sagar Vijay Mehra, N. S. Neki
Keywords
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- EP ID EP550080
- DOI 10.22192/ijcrms.2017.03.03.008
- Views 138
- Downloads 0
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