Incidence of AKI with or without hemodialysis in tribal population of Chhattisgarh
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2019, Vol 9, Issue 1
Abstract
The information regarding the incidence of acute kidney injury (AKI) with or without haemodialysis in tribal population of Chhattisgarh is limited. The aim of the study was to find the incidence, prognostic factors, and outcome of patients with AKI. We also assessed whether only urine output criteria of risk, injury, failure, loss, end (RIFLE) classification can be used to look at the outcome of AKI. Acute kidney injury (AKI) is a common clinical problem in the community and especially in critically ill patients and is associated with an increase in morbidity and mortality, reduction in glomerular filtration rate (GFR) over a short time period, is a common and severe complication in patients with cirrhosis and is often triggered by a precipitating event (i.e. overdose of diuretics, large-volume paracentesis without albumin replacement, gastrointestinal bleeding, bacterial infections, Better classification of renal failure by the risk, injury, failure, loss, end stage (RIFLE), and Acute Kidney Injury Network (AKIN) guidelines has made the reports more standardized. The incidence of AKI is associated with mortality as high as 45–50%, with dialysis dependence, with reduced quality of life, and with excess utilization of health resources. All patients underwent HD. Based on our study, prediction of the requirement of RRT-based on admission values of bilirubin, sepsis, and metabolic acidosis does not seem to be valid. Only creatinine on admission, increasing age, APACHE II, SOFA score, and use of noradrenaline were significantly associated with the requirement of HD in multivariate analysis. The incidence of AKI was 12.35% in critically ill patients. In patients with AKI, 29.03% patients required HD and 28 day mortality was 58.06%. AKI patients with septic shock with vasopressors have a higher requirement of RRT, especially as age increases
Authors and Affiliations
Ashish D, Dr. Punit G, Ghanaram S, Vijay B
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