INCIDENCE OF VIRILISATION IN SEX CORD STROMAL TUMOURS OF OVARY, A 5- YEAR EXPERIENCE IN A TERTIARY CARE GYNAECOLOGICAL CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 7
Abstract
BACKGROUND Androgen secreting ovarian tumours represents less than 5% of all ovarian neoplasms. Hyperandrogenism results in development of acne, hirsutism, androgenic alopecia, menstrual irregularities & virilisation or masculinization. The objective of this study is to look for incidence of virilisation in sex cord stromal tumours and discussion regarding various causes of hyperandrogenism. MATERIALS AND METHODS A retrospective descriptive study of virilising tumours of ovary was conducted in a tertiary care gynaecological centre at Institute of obstetrics and Gynaecology, Chennai for a period of 5 years from February 2012 to February 2017. 4 cases of sex cord stromal tumours presented with signs of virilisation. RESULTS A total of 592 ovarian malignancies were identified over a period of 5 yrs. out of which 36 cases were diagnosed as sex cord stromal tumours (6.08%). The most common age group affected are between 41 to 50 yrs. with median age of 45 yrs. Right sided ovary (58%) is more commonly involved than left sided (42%) ovary. Most of the tumours were solid in appearance with average size ranging between 6 cm – 10 cm. The most common symptom is abdominal mass (64%) with 4 cases presented with history of virilisation (11%). CONCLUSION Based on present study it may be concluded that patients with symptoms of virilisation require detailed clinical history, physical examination for signs, laboratory investigations & imaging to exclude causes other than ovarian neoplasm.
Authors and Affiliations
Mahendran Revathy, Madurai Padmanabhan Kanchana
Keywords
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- EP ID EP399094
- DOI 10.14260/jemds/2018/202
- Views 90
- Downloads 0
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