Induced pluripotent stem cells in infections
Journal Title: International Journal of Blood Transfusion and Immunohematology - Year 2015, Vol 5, Issue 1
Abstract
Aims: Blood transfusion is an essential management to save patients life in health care system. Blood is a potential source of transmitted diseases which make the safety of blood products important issue in laboratory medicine. Investigations of transfusion-transmitted infections (TTI), especially hepatitis viruses and acquired immunodeficiency virus, are essential in all blood bank policies. Several methods were applied to screen blood products for hepatitis B and hepatitis C viruses and acquired immunodeficiency virus. Methods: Blood donor's samples for one year were collected and examined for hepatitis viruses and acquired immunodeficiency virus by using serological and nucleic acid testing (NAT). Results: Comparative study showed that NAT is more specific than serologic screening testing for both hepatitis C virus and acquired immunodeficiency virus. However, NAT and serological tests are required to increase the safety of blood components from hepatitis B virus transmission. Conclusion: This study is an attempt to evaluate the effectiveness of introducing NAT for examination of blood components. National-wide study is required to evaluate the policy of blood screening program.
Authors and Affiliations
Anubha Singh, Deepak Kumar Singh, Usha Bhoria
Keywords
Related Articles
- EP ID EP209973
- DOI 10.5348/ijbti-2015-17-RA-3
- Views 165
- Downloads 0
Comparative study of two automated pre-transfusion testing systems (microplate and gel column methods) with standard tube technique
Aims: Clinically significant antibodies may become undetectable and still provoke transfusion reactions. Hemolysis has been reported among transfusion recipients with anti-Kidd that was undetectable by gel column but det...
Pattern of blood donor deferral in a tertiary hospital, South-south, Nigeria: A three-year study review
Aims: Provision of safe and adequate supply of blood and blood products is a major public health issue globally. Safe blood is ensured through proper donor selection and testing of donated blood. However, a large number...
Detection sensitivity of red cell alloantibodies using microtube column agglutination systems
No Abstract
The prevalence of transfusion transmitted infections: A focus on hepatitis B virus among blood donors at Hawassa blood bank center, Southern Ethiopia
Aims: Millions of lives are saved each year through blood transfusion but a safe blood supply is a critical component of health care to prevent the spread of blood-borne infectious diseases. Therefore, it is essential to...
Lifetime risk and characterization of red blood cell alloimmunization in chronically transfused patients with sickle cell disease
Aims: Patients with sickle cell disease (SCD) are often exposed to multiple units of blood transfusions predisposing them to the development of alloantibodies. Alloantibodies make subsequent transfusion difficult, costly...