Inflammation in Chronic Hepatic Diseases and Possible Approaches to the Treatment
Journal Title: Гастроентерологія - Year 2014, Vol 1, Issue 51
Abstract
Inflammation reactions are the central component of liver regeneration after injury of various etiologies. The realization of these reactions involves a large number of pro-inflammatory cytokines: interferons, interleukins, tumor necrosis factors, transforming growth factors, colony stimulating factors, and chemokines. Thus, the study of different ways to influence the specific mediators of inflammation and inflammatory process in general today is a promising direction in developing strategies for the management of patients with inflammatory diseases of the liver. There remains topical the question of the appropriateness of application in this category of patients of various kinds of pathogenetic therapy agents, traditionally called hepatoprotectors. This article deals with a detailed analysis of the mechanisms of chronic inflammation in hepatitis of various etiologies, some aspects of the diagnosis of above diseases and studying the efficacy of pathogenic anti-inflammatory therapy with the definition of its place in the treatment of such pathology.
Authors and Affiliations
V. V. Chernyavsky, A. K. Sizenko, L. S. Gvozdetskaya
Keywords
Related Articles
- EP ID EP225047
- DOI -
- Views 98
- Downloads 0
Indicators of Ultrasonic Histography of the Pancreas in the Dynamics of Treatment of Patients with Chronic Pancreatitis on the Background of Obesity
In this article the authors presented the results of own research of patients with chronic pancreatitis on the background of obesity. In treatment of such patients it is reasonable to include cardonat and cefasel as they...
Morphological and Biochemical Evaluation of Progression of Chronic Hepatitis Associated with C Virus
The article deals with the morphological features of the liver tissue and changes in the metabolism of extracellular matrix components during progression of chronic hepatitis C. There has been carried out the comparison...
Pathogenetic aspects of chronic pancreatitis and chronic obstructive pulmonary disease comorbidity
A review of the literature considers the question of the involvement of certain mechanisms in the comorbid course of chronic pancreatitis with chronic obstructive pulmonary disease (COPD). Attention is drawn to the fact...
Functional Dyspepsia in the Light of the Rome IV Criteria
The article deals with the problem of functional dyspepsia. The pathophysiology is described in detail, the diagnostic criteria of this disease are given, the aspects of treating patients with functional dyspepsia are co...
Treatment of Anemia in Patients with Inflammatory Bowel Diseases
Anaemia is a frequent systemic manifestation of inflammatory bowel diseases (IBD) which has significant impact on the quality of life, is associated with severity of disease and resistance to therapy. Anaemia in IBD is m...