INFLAMMATORY FACTORS AND ENDOTHELIUM FUNCTION AMONG ADULT MEN WITH DIFFERENT PHYSICAL ACTIVITY

Journal Title: Medycyna Sportowa - Year 2006, Vol 22, Issue 2

Abstract

Background. Favourable influence of physical activity on prevention of future cardiovascular events was proven. The origin of this phenomenon hasn't been yet explicitly defined. Probably one of the most important factors is the beneficial influence of physical activity on endothelium function. The main goal of the study was to determine the correlation between endothelial function, the presence of the chronic inflammatory state in blood vessels and physical activity and cardiorespiratory fitness among clinically healthy men.Material and methods. The study included 60 adult men, divided in two groups, according to energetic expenditure on leisure time physical activity. The border line was 1000 kcal/week. The mean age of the two groups was similar: 54,0±8,5, 53,8±6,1 years (p>0,05). Physical activity assessment was carried out by The Seven Day Physical Activity Recall. Endothelium function and the presence of inflammatory state were estimated by hs-CRP, sICAM-1, sE-sel assignment in serum using standard ELISA kits. Some selected risk indicators of chronic cardiovascular and metabolic diseases like: glycaemia, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides were estimated as well as basic anthropometric parameters. The results of the study were correlated with cardiorespiratory fitness determined by VO2max indirectly calculated using Astrand-Rhyming nomogram.Results. hs-CRP concentration as well as sICAM-1 and sE-sel among men having week energy expenditure above 1000 kcal was lower than among man not undertaking regular physical activity (week energy expenditure below 1000 kcal), however the difference was not significant: 1,4±1,3 vs 1,9±1,5 mg/l (p>0,05), 308,5±79,5 vs 343,6±86,3 ng/ml (p>0,05), 48,7±25,8 vs 49,0±24,3 ng/ml (p>0,05). The correlation between physical efficiency and concentration of hs-CRP, sICAM-1 and sE-sel was not observed. Conclusions. Based on the results it may be assumed that systematic physical activity influences to some extent endothelium function and chronic inflammatory state in blood vessels among adult men.

Authors and Affiliations

Anna Jegier, Monika Nonas

Keywords

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  • EP ID EP55500
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How To Cite

Anna Jegier, Monika Nonas (2006). INFLAMMATORY FACTORS AND ENDOTHELIUM FUNCTION AMONG ADULT MEN WITH DIFFERENT PHYSICAL ACTIVITY. Medycyna Sportowa, 22(2), -. https://europub.co.uk./articles/-A-55500