Inhibition efficiency of urine towards stone forming minerals.
Journal Title: International Journal of Pharma Sciences and Research - Year 2010, Vol 1, Issue 1
Abstract
Urine specimens were collected from 100 normal individuals and 100 kidney stone patients and analysed spectrophotometrically for common stone promoters like oxalate, calcium, uric acid and phosphate and stone inhibitors like citrate and magnesium. Inhibition efficiency by these inhibitors exiting in urine samples towards the mineralisation of urinary stone forming minerals like calcium oxalate ,phosphate or carbonate has been studied in an experimental model. The results were presented as mean ± SD, student’s t test was used for statistical analysis. Hypocitraturia and hyperoxaluria were the common abnormalities in the stone formers. Kidney stone patients had significantly higher urinary oxalate, calcium and uric acid and lower phosphate than normal individuals. The efficiency is markedly higher for phosphate, carbonate and urates by healthy urine samples.For the stubborn mineral oxalate has low inhibition efficiency. The urine of stone formers show very little inhibition. This implies that inhibition of crystal growth is proportional to the concentration of inhibitory factor present.
Authors and Affiliations
Dr. Seema Jawalekar , Dr. V. T. Survey , Dr. Anil K. Bhutey
Keywords
Related Articles
- EP ID EP144717
- DOI -
- Views 125
- Downloads 0
Method Development and Validation for The Simultaneous Estimation of Ofloxacin and Ornidazole in Tablet Dosage Form by Rp-Hplc
A simple reverse phase liquid chromatographic method has been developed and subsequently validated for simultaneous determination of Ofloxacin and Ornidazole in combination. The separation was carried out using a mobile...
Aloe vera: Plant of Immortality
The Egyptians called Aloe the “Plant of Immortality” because it can live and even bloom without soil. Aloe has been used medicinally since at least the first century C.E. and continues to be used extensively worldwide....
Hepatoprotective Activity of Leucas lavandulaefolia Against Carbon tetrachloride-Induced Hepatic Damage In Rats
The aerial parts of [i]Leucas lavandulaefolia[/i] Rees, family Labiatae was tested for hepatoprotective activity against CCl4 in rats. The ethyl acetate extract of [i]Leucas lavandulaefolia[/i] has shown significant act...
Homology Modelling and Insilico Analysis of Hemagglutinin Protein from H1n1 Influenza A Virus
World wide spread of H1NI Influenza A Virus has raised concerns. Modelling of Hemagglutinin protein of Influenza A virus (A/Sakai/1/2009(H1N1)) Hemagglutinin (HA) protein was done using Modeller 9V2. Modelled structure w...
Does screening of pregnant women prevent mother to child transmission of HIV?A study in nsukka urban area of Enugu State, Nigeria.
[b]Background:[/b] One of our best opportunities for progress against AIDS lies in preventing mothers from passing on the HIV virus to their children. Worldwide, close to 2,000 babies are infected with HIV every day, dur...