Inhibitory effects of cinnamon-water extract on human tumor cell lines
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2014, Vol 4, Issue 0
Abstract
Objective: To question the inhibitory effect of cinnamon-water extract (CWE) on four human tumor cell lines (AGs, HeLa, MCF-7 and MDA-MB234). Naturally, compounds are an important source for clinical proposes. Cinnamon, a plant-derived spice, is widely used as a food additive and has been attracted many researches in recent years to find its pharmaceutical benefits. Methods: In order to find the answer to this subject, the water extract of cinnamon was prepared and cell proliferation was evaluated using MTT assay. The effect of apoptosis was investigated by DNA fragmentation analysis. Results: The inhibitory effect of CWE on the growth of the cells was significant. DNA fragmentation was found in cultured AGs and MCF-7 cell lines treated by CWE. Conclusions: This study showed the anti-neoplastic activity of CWE on tumor cell lines
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- EP ID EP230905
- DOI 10.1016/S2222-1808(14)60768-4
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