Insight into Vitamin D Deficiency: an obstretical outlook
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2017, Vol 4, Issue 4
Abstract
Vitamin D deficiency has been linked with various adverse health outcomes as a result of which it attracts the attention in research field in current days. In this way, Vitamin D deficiency has influenced upon adverse pregnancy outcomes. Over the last decade studies have been done with systematic reviews and meta analysis in epidemiologic literature. (1,2) Likewise, it is gaining importance over its classical action in health in recent era as it has some non-classical actions such as immunomodulation, anti-inflammatory, insulin secretion enhancement etc. (3) Vitamin D, pleotropic secosteroid hormone has two forms: 1. Vitamin D3 or chloecalciferol 2. Vitamin D2 or Ergocholecalciferol Cholecalciferol is produced from 7- Dehydrochloecalciferol in skin and the second one ergocalciferol is the produced in the mushrooms and yeast. (4) In the liver vitamin D is changed to calcidiol and calcidiol is converted to calcitriol in kidney by various enzymatic reactions. (4) Calcidiol being the major circulating form represents most appropriate nutritional status. On the other hand, calcitriol is the active form of vitamin D.
Authors and Affiliations
Savita Rani Singhal, Bhupali Das
Keywords
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