Insulin Resistance and its Correlation with Risk Factors for Developing Diabetes Mellitus in 100 Omani Medical Students
Journal Title: Sultan Qaboos University Medical Journal - Year 2014, Vol 14, Issue 3
Abstract
Objectives: Te aim of this study was to assess the prevalence of insulin resistance (IR) in healthy young Omanis and relate this with their body mass index (BMI) and family history (FH) of diabetes mellitus (DM). Methods: Tis study was conducted between May 2009 and February 2010 at Sultan Qaboos University, Muscat, Oman. A detailed questionnaire was completed by 50 male and 50 female medical students between 20–25 years old. Fasting blood samples were obtained for serum glucose and insulin measurements. IR was calculated using the homeostasis model assessment-estimated insulin resistance (HOMA-IR) formula (fasting insulin x fasting glucose/22.5) and a value above 2.5 was considered elevated. Te results were analysed using the Statistical Package for the Social Sciences (SPSS). Results: Participants were classifed into the following BMI categories: 59% were normal (18.5–24.9 kg/m2), 26% were overweight or obese (>24.9 kg/m2) and 15% were underweight (<18.5 kg/m2). A FH of DM was present in 74%. Te HOMA-IR index was elevated in 16% and was directly correlated to the BMI (P = 0.003). Tere was no correlation between IR and a positive FH of DM. Conclusion: Tere is a high prevalence of IR (16%) and obesity (26%) in healthy young Omani medical students. Counselling is recommended for all overweight and obese individuals in an attempt to prevent or delay the onset of DM in the future.
Authors and Affiliations
Humaid H. Al-Farai| Department of Surgery, Sultan Qaboos University Hospital, Issa Al-Aboodi| Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Azza Al-Sawaf| Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Noora Al-Busaidi| Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman, Nicholas Woodhouse| Department of Medicine, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman
Keywords
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