Intra-operative squash cytodiagnosis of pleomorphic xanthoastrocytoma : A diagnostic challenge
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2017, Vol 4, Issue 4
Abstract
Pleomorphic xanthoastrocytoma (PXA) is WHO grade II tumor representing less than 1% of all astrocytic tumors. It displays cellular atypia and pleomorphism to such an extent that it can be misdiagnosed as a high grade glioma thereby posing a diagnostic challenge especially during intraoperative squash preparations. The present case is a 16-yr-old boy with history of seizures and CT Brain showed a mass located in the right temporal lobe. The intraoperative cytological diagnosis of low grade glioneuronal tumor was rendered.Pleomorphic xanthoastrocytoma was confirmed on histopathology and immunohistochemistry. This challenging case highlights the salient cytomorphologic features of this tumor along with differential diagnosis.
Authors and Affiliations
Rachana Binayke, Shubhangi Vinayak Agale, Geeta Kumari, Grace. F. D'Costa
Keywords
Related Articles
- EP ID EP281810
- DOI 10.17511/ijpr.2017.04.07
- Views 127
- Downloads 0
Low birth weight newborn: epidemiological, therapeutic and evolutive aspects in the commune of Kara (TOGO) from 2014 to 2015
Introduction: Low birth weight (LBW) is the third leading cause of neonatal death after neonatal infections and asphyxia. Objective: Describe the epidemiological, therapeutic and evolutionary effects of LBW neonates. Met...
A comparison study of blood lactate and lactate clearance with SNAP II score as predictors of outcome in sick neonates
Introduction: Necessity of longer stay in NICU reinforces the need for more sensible and specific parameter to evaluate the length of stay and outcome. In order to improve the clinical outcomes in sick neonates, it is cr...
Evaluation of the benefits and efficacy of light emitting diode (LED) device with respect to conventional fluorescent tube phototherapy device in neonatal hyper bilurubenimia in near term and full term neonates
Introduction: Neonatal jaundice is a common, in most cases a benign problem in neonates. About 60% of term and 80% of preterm babies develop jaundice during the first week of life. About 5-10% of all newborns need photot...
Knowledge attitude and practices of childhood diarrhea and ORS administration in diarrhea amongst mothers of children below age 5 years: A hospital based cross-sectional survey
Introduction: Basic minimal information about care of children in diarrhea and ORS use is necessary for early recovery. To plan anti diarrheal program, its important to know the knowledge, beliefs, practices of diarrhea...
Randomized controlled trial of the impact on the outcome of pneumonia in children receiving Vitamin D supplementation
Objective: To study whether vitamin D supplementation in children presenting with pneumonia and severe pneumonia reduce its duration of recovery. Study design: Randomized, Double blind, Placebo-controlled trial. Setting:...