Intracerebral Primary Benign Chondroblastoma: Report of a Rare Case
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Chondroblasoma (CB) is a rare benign cartilaginous bone tumor arising from the epiphysis of long bones. Even rarer is intracerebralchondroblastoma. We report a unique case of primary benign chondroblastoma in left frontal lobe of cerebrum in 23 year-old male. He presented with intermittent frontal headache and vomiting of two weeks duration. Radio-imaging suggested the possibilities of meningioma and oligodendroglioma.The tumor was completely excised through left frontal craniotomy. Intra-operative squash smears revealed a benign, non-glial tumor with osteoclastic giant cells. Histologic examination showed typical features of benign chondroblastoma. On Immunostainingchondroblasts exhibited strong reactivity for S-100 protein and Vimentin. Osteoclastic giant cells were strongly positive for CD68. Tumor cells were negative for GFAP and EMA. To the best of our knowledge, this is the second case report of primary intracerebralchondroblastoma in the English literature. Here we discuss the differential diagnosis and probable histogenesis of intracerebral primary chondroblastoma.
Authors and Affiliations
Purwa R. Patil, Bhushan M. Warpe, Asif A. Khan, Shantilal Sisodiya
Keywords
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- EP ID EP415537
- DOI 10.9790/0853-1711066974.
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