Intralesional Bleomycin for Lymphangioma: An Effective Alternative Non-surgical Therapy
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2019, Vol 6, Issue 10
Abstract
Introduction: Conventionally, lymphangiomas have been managed by surgical excision which range from simple excision to extensive compartmental exenteration.With the advent of the usefulness of sclerotherapy, especially bleomycin, management of extensive lymphangiomas which are hitherto considered inoperable cases has become very comfortable for patient and surgeon. Materials and Methods: A total of 28 patients were included in the study. Neck was the most common site of involvement followed by axilla; groin was involved in two cases. Injection bleomycin was reconstituted and diluted, a dose of 0.5 IU/Kg injected intralesionally after aspirating an equal volume of fluid. Compression bandage was applied for 24 h. Cases were reviewed after 3 weeks for assessing clinical and serological response. Results: Significant reduction of mass was noted in 68% of cases (n = 19). Surgery was required in 7% (n = 2), complete regression of mass was noted in the remaining 25% (n = 7) cases. Conclusion: This modality of treatment may be used safely as primary modality of treatment for select group of patients.
Authors and Affiliations
Damisetti Kalyan Ravi Prasad, Jeeru Bhaskar Reddy
Keywords
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