Intranasal dexmedetomidine vs intranasal midazolam for premedication in paediatric patients undergoing surgery under general anaesthesia
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction This prospective randomized doubleblind study was conducted with an aim to compare the efficacy of intranasal dexmedetomidine and intranasal midazolam as premedication in uncooperative children undergoing elective surgery under general anaesthesiaMaterials and Methods One hundred and twenty children in American Society of Anesthesiology classification ASA physical status I II in the age group of 212 years who were planned to undergo surgery under general anaesthesia were included in the study and were randomly assigned to one of the two groups Group D received 1 mcgkg of IN dexmedetomidine while group M received 02 mcgkg of IN midazolam for premedication The patients sedation status separation anxiety and mask acceptance along with the hemodynamic parameters were notedResults Satisfactory sedation was achieved in 56 children in group M and 65 children in group D p 005 Compared with the children in group M those in group D had significantly better satisfactory anxiolysis at the time of separation from the parents 56 vs 50 p 0Conclusion Intranasal midazolam and dexmedetomidine are both effective as premedication in children undergoing surgery However intranasal dexmedetomidine offers better effect on sedation alleviating separation anxiety and acceptance of facemask during induction than intranasal midazolamKeywords Intranasal Dexmedetomidine Midazolam
Authors and Affiliations
Amit Rai, Josemine Davis, Thaneshwar Rijal,
Keywords
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- EP ID EP476462
- DOI 10.18231/2394-4994.2018.0061
- Views 71
- Downloads 0
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