Intravenous Drug Use Rates and Results of Direct-acting Antiviral Treatment in Prisoner Patients
Journal Title: Viral Hepatitis Journal - Year 2020, Vol 26, Issue 2
Abstract
Objectives: Intravenous drug use (IVDU) is more common in prisoner patients, and this is a global problem. Hepatitis C virus (HCV) infection is higher in prisoners than general population. In our study, we aimed to examine the IVDU rates and direct-acting antiviral (DAA) treatment results of the prisoners who applied to Hatay Mustafa Kemal University Clinic of Infectious Diseases. Materials and Methods: In our study, IVDU rates and HCV treatment results of 85 prisoners who applied to Hatay Mustafa Kemal University Faculty of Medicine Clinic of Infectious Diseases between January 2017 and December 2019 were retrospectively analyzed. Treatment results were evaluated by performing modified intention to tract (mITT) and per protocol (PP) efficacy analysis, respectively. Results: The rate of IVDU was 37.7% in prisoners who were positive for HCV. Although sustained virological response (SVR) rate was 100% in PP analysis, SVR rate was determined as 80.5% in mITT analysis. Viral genotype 3 (41.6%) and genotype 4 (39%) were the most common. Conclusion: However, data on HCV screening and treatment in prisons in Turkey is inadequate or too low. We think that with the use of DAAs, patients’ compliance to treatment will increase, it is an important step for HCV eradication and multicenter studies should be conducted.
Authors and Affiliations
Mehmet Çabalak, Tayibe Bal
Keywords
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- EP ID EP688800
- DOI 10.4274/vhd.galenos.2020.2020.0015
- Views 110
- Downloads 0
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