Investigation of Biosynthesized Silver Nano Particles Interaction From Halymenia Porphyroides With The E7 Protein Using Bioinformatics Tool
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Silver nano particles have known to possess anticancer properties in the early stages of virus proliferation. In the present study biosynthesis of silver nano particles from marine red alga Halymenia porphyroides was synthesized and characterized. Studies on protein disulphide bonds were done using Metal Detector Predicts V2.0 software. All Cys and His residues in amino acid sequences were identified. The study revealed that silver nano particles couple with the sulfhydryl groups led to decrease the disulphide bonds and denatures the E7 protein thus eliminating the possibility of the occurrence of the disease. Nano particles exhibit unique biological, physical and chemical properties based on specific characteristics such as shape, size, distribution and surface morphology. Synthesis of nano particles through biochemical routes, using plant and algal extracts as reducing and capping agents, has received special attention among others, due to maintaining an aseptic environment during the synthetic process [1-7]. Therefore, medicinal plants and algae having well established therapeutic importance are being widely used for the size and shape controlled synthesis of silver nano particles [8-11]
Authors and Affiliations
Vishnu Kiran M, Murugesan S, Sivamurugan V
Keywords
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- EP ID EP570090
- DOI 10.26717/BJSTR.2017.01.000359
- Views 172
- Downloads 0
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