Investigation of Total Phenolic, Flavonoid Contents and Antioxidant Activity from Extracts of Azadirachta indica of Bundelkhand Region
Journal Title: SSR Institute of International Journal of Life Sciences (SSR-IIJLS) - Year 2018, Vol 4, Issue 4
Abstract
Azadirachta indica common name Neem is a very useful traditional medicinal plant in the sub-continent and each part of the tree has some medicinal properties. It has many therapeutic properties as it boosts the immune system, beneficial in treating acne, provides relief from bad breathe, helps to protect against diabetes, effective in treating malaria symptoms, lowers the risk of cancer and cardiovascular disease. The plant is native to Asia and its sub-continents. Therefore, the aim of the present study was to investigate the phytochemical constituents present in leaves and bark of neem. The antioxidant activity, total phenolic, and flavonoid contents were also evaluated. Neem leaves and bark were collected from the Bundelkhand University Campus, Jhansi. It was cleaned with tap water and finally with distilled water and was air dried at room temperature and crushed. TLC was done for the determination of bioactive compounds present in the leaves. A qualitative phytochemical analysis was performed and we found that alkaloids, reducing sugar, flavonoids, glycosides, tannins, phenolic compounds, saponins are present in neem leaves and bark. TLC results shown total 8 spots in the methanolic leaves extract having different Rf values. The total antioxidant capacity of A. indica leaves shown the dose dependent activities. The mean values of total phenolic contents and flavonoids are 70 mg GAE/g & 119 mg QE/g respectively. Thus in the present study, the presence of flavonoids and phenolic compounds in the neem leaves extract could be considered responsible for conferring antioxidant ability.
Authors and Affiliations
Ramesh Kumar, Smrati Sharma, Laxmi Devi
Keywords
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- EP ID EP671028
- DOI 10.21276/ijlssr.2018.4.4.10
- Views 86
- Downloads 0
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