Invitro Anti-Inflammatory Activity of Anacardium Occidentale Seed Extract.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 1
Abstract
Anacardiumoccidentale (Cashew) is a plant native to Brazil, but is cultivated in tropical regions worldwide. It was imported to India by Portuguese. According to the FAO, India is one of the top five producers of cashew in the world. Antibacterial, antidiarrheal, anti-ulcerogenic, wound healing, anticancer and antioxidant activities of extracts and phytochemical derivatives from Anacardiumoccidentale have been reported by different authors. In this study we evaluated that anti-inflammatory activity of Anacardium occidentale seed extract "In vitro" using HRBC membrane stabilization method and Protein denaturation using egg albumin method. The EEAOS (EthanolicExtract of AnacardiumoccidentaleSeed)extractshowed dose dependent percentage inhibition of HRBC (Human Red Blood Cell) membrane lysis and inhibition of protein denaturation. EEAOS extract exhibited membrane stabilization effect at 150 and 200 µg/ml have antiinflammatory activity and it is almost equal to Diclofenac at 200 µg/ml. At 200 µg/ml dose EEAOS extract has almost equal inhibition of protein denaturation action like that of diclofenac.
Authors and Affiliations
G. Rajeswaramma, D. Jayasree
Keywords
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