Iron Status in Preeclampsia – A Study from South India
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 8
Abstract
Preeclampsia is one of the major causes of maternal and fetal morbidity and mortality. Though the etiology is obscure, studies indicate the role of increased oxidative stress due to endothelial dysfunction in preeclampsia. The aim of this study was to find out iron status parameters in preeclamptics and their comparison to normotensive pregnancies. This study was done in a medical college hospital in South India. 60 women with preeclampsia and 60 normotensive pregnant women were analyzed for serum iron, ferritin and hemoglobin levels. Pregnancy outcome in both groups were compared. Data were expressed as Mean ± Standard Deviation. Comparison of serum levels of the elements was performed by Independent t test and Chi square test and P value of < 0.05 was considered as statistically significant. Mean serum iron and ferrtin levels in preeclamptics were significantly higher compared to normotensives whereas hemoglobin levels did not show much difference. Also preeclamptic women were older, with higher BMI and lower birth weight compared to normotensives. The higher serum iron and ferritin levels might play an important role in the etiopathogenesis of preeclampsia. Therefore, pregnant women with higher serum iron and ferritin levels should be investigated for preeclampsia. Iron status of pregnant women should be assessed before giving iron supplements as these may cause more harm than benefit
Authors and Affiliations
Dr. Deepa V Kanagal
Keywords
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