Is Homocysteine a silent marker for cardiovascular disease?
Journal Title: International Journal of Biomedical and Advance Research - Year 2017, Vol 8, Issue 12
Abstract
Background: Cardiovascular disease (CVD) remains one of the leading causes of morbidity and mortality in India. Association between hyperhomocysteinemia and Metabolic Syndrome (MS) or its components in a population with or without cardiovascular disease is not well established. This study aims to check levels of homocysteine (Hcy) and its relationship with CVD. Aims and Objectives: To check Hcy levels in healthy adults and MS patients to reflect its association with CVD. Material and Methods: Case control study was done on 40 subjects patients with MS (n=20) and controls (n=20) of 30 - 60 years at Fr. Muller Medical College Hospital, Karnataka. Results: Homocysteine levels were significantly higher in MS group when compared to controls (p = 0.04). Conclusion: MS group had higher homocysteine levels along with blood glucose, triglycerides, total cholesterol when compared to controls. Elevated levels of Hcy can be a marker for cardiovascular disease. Furthermore, the results of this study suggest the overall role of homocysteine function on insulin resistance, and its association with cardiovascular parameters.
Authors and Affiliations
Nithin Varghese Abraham, Priyanka S. Bannikoppa, Pauline Anand
Keywords
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- EP ID EP384624
- DOI 10.7439/ijbar.v8i12.4515
- Views 83
- Downloads 0
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