Abstract

Objective: To determine the incidence of leptospiral jaundice and find the correlation among human leptospiral cases with or without jaundice. Methods: Patients suspected for leptospirosis, attending Calcutta School of Tropical Medicine, Kolkata, India during 2002 to 2008 were evaluated as per modified Faine ’s criterion. Results: Out of 404 suspected cases, 214 were found positive for leptospirosis, 15 were jaundice positive but without leptospirosis and 175 cases had neither leptospirosis nor jaundice. Serum bilirubin and creatinine levels among leptospirosis patients were (1.89-42.70 mg/dL) and (0.60-6.40 mg/dL), respectively; serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) were (99.00-410.00 U/L) and (57.00-887.00 U/L), respectively; IgM values by ELISA were (0.63-3.28 U/mL). Conclusions: There is no association between occurrence of jaundice and leptospirosis and it also does not confirm the expected 1:1 ratio of jaundice and leptospirosis (P<0.005).

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