IS THERE ANY LINK BETWEEN A KIND OF THYROCYTE DYSFUNCTION, HYPOTHYROIDISM, AND INFLAMMATORY HEMATOLOGIC PARAMETERS IN THE CASES POSSESSING THE BENIGN THYROID NODULES? A 5-YEAR SINGLE-CENTRE EXPERIENCE
Journal Title: SANAMED - Year 2018, Vol 13, Issue 1
Abstract
Objective: Microscopically, the thyroid gland is composed of spherical follicles and thyroid parenchyma includes two major cell types, the thyrocytes releasing thyroid hormones and C cells secreting mature calcitonin. Hypothyroidism has been known as being associated with the various abnormalities of the coagulation system. In the present study, it had been purposed to inverstigate the relationship between inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW and hypothyroid hormonal status in the cases possessing the benign thyroid nodules. Material and Methods: A total of 313 cases, 202 with hypothyroidism, 111 with euthyroidism possesing the benign thyroid nodules, that was verified with the cytological evaluation after one-endocrine surgeon performed ultrasonography (US) guided fine needle aspiration (FNA) (US-g-FNA), at the Division of Endocrine Surgery, Department of General Surgery, Giresun University Faculty of Medicine, Giresun, Turkey, in conformity with the criteria, were enrolled into the study during the period, from April 2010 to April 2015. The documents that were used to follow consisted of laboratory tests of the cases including both the thyroid hormones, freeT3, FreeT4, and TSH, and the inflammatory hematological parameters were reviewed and scanned retrospectively. The upper limit of the normal Thyrotropin (TSH) reference range was determined as 4 mU/L in the present study. Results: No statistically significant difference was found between the inflammatory hematological parameters, RBC, Hb, Htc, RDW, WBC, neutrophil, lymhocyte, N/L, Plt, MPV, PCT, PDW, and hypothyroidism (p>0.05). Conclusion: Inflammatory hematological parameters may not be useful for estimating the hormonal status of the thyroid gland in the cases with the benign thyroid nodules verified with the cytological evaluation, TBSRTC.
Authors and Affiliations
Demet Sengul, Ilker Sengul
Keywords
Related Articles
- EP ID EP348396
- DOI 10.24125/sanamed.v13i1.211
- Views 156
- Downloads 0
BIBLIOGRAPHY OF SANAMED JOURNAL (2014-2017)
This paper presents a bibliography of Sanamed, journal of medical and health science, founded by a group of doctors from Novi Pazar. The Journal published original articles, case reports, literature reviews, articles on...
PURE RED CELL APLASIA INDUCED BY ERYTHROPOIETIN
Introduction: Recombined human erythropoietin has been present in clinical practice for more than 20 years, in these therapeutic indications: anemia in kidney insufficiency, anemia during chemotherapy of tumors, preventi...
EVALUATION OF A PROGRAM OF PHYSICAL ACTIVITIES ADAPTED TO THE MORPHOLOGICAL, PHYSIOLOGICAL AND BODY COMPOSITION PARAMETERS OF OVERWEIGHT AND OBESE ADOLESCENTS OF THE LUKUNGA SPORTS CLUB OF KINSHASA, DEMOCRATIC REPUBLIC OF CONGO
Objective. To study the effects of regular physical activity on the morphological, physiological and body composition parameters of overweight and obese adolescents.Methods. We conducted an experimental study with30 adol...
ELECTROSURGICAL MICRONEEDLE VERSUS SCALPEL SKIN INCISIONS IN THE FACIAL REGION
Objective: Electrosurgery is widely used in surgical procedures, but mainly for subcutaneous and deep layer dissections. The aim of this study was to clinically evaluate the results of routine use of electrosurgical micr...
A STUDY ON THE EFFECTIVENESS OF CLOMIPHENE CITRATE IN COMPARISON TO GNRH ANTAGONIST IN PREVENTING LH SURGE AMONG PATIENTS UNDERGOING OVULATION INDUCTION IN IVF-ICSI
Objective: To determine the efficacy of clomiphene citrate (CC) in preventing luteinizing hormone (LH) surge without adding gonadotropin releasing hormone (GnRH) antagonist or GnRH agonist in stimulated first fresh intra...