Ischemic stroke of undetermined etiology in a 14 year old girl
Journal Title: MedPulse -International Medical Journal - Year 2014, Vol 1, Issue 9
Abstract
Ischemic stroke is the most common cerebrovascular disease, most often due to atherothrombotic diseases and uncommonly by disorders of hypercoagulation. Disorders of coagulation and associated thrombotic disorders account for approximately 1% of all ischemic strokes and 4-8% of strokes among younger people. Similarly combined deficiency of protein C and S along with increased levels of homocystine and factor 5 mutation can lead to hypercoagulable state and rarely present as cerebrovascular accident. Stroke is not common in the young patients but when it occurs due to rare causes of hypercoaguable states warrants for different approach for investigation and management. Here we describe a case report of stroke in a 14 year old girl. It is emphasised that Protein C deficiency though rarely associated with thrombotic events but when dealing with a case of cerebral infarction (arterial thrombosis) in young patient, screening for Protein C and S should be made, especially when patients are below 45 years, have a personal history of recurrent thrombosis without precipitating factors, thrombosis in unusual sites, thrombosis during pregnancy, a positive family history of thrombosis.
Authors and Affiliations
Shoeb Khan, Abdul Rafe Abdul Qadeer
Keywords
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