ISOLATION AND CHARACTERIZATION OF MUCILAGE FROM THE FRUIT PULP OF FERONIA LIMONIA
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2015, Vol 6, Issue 7
Abstract
Development of new excipients is time consuming, involves tedious procedures and is highly expensive. Instead, identification of new uses for the existing substances is relatively inexpensive and less time consuming. The intention of present study was designed for isolation and characterization of mucilage from the fruit pulp of Feronia limonia and explores its use as pharmaceutical excipient. Mucilage was isolated by maceration technique using distilled water and precipitated with acetone as a non-solvent. The isolated mucilage was investigated for purity by carrying out chemical tests for different phytochemical constituents and only carbohydrates were found to be present. The mucilage was further characterized for physical and flow properties. It had good swelling index (19.16) and pH was found to be 4.25. The mucilage powder had poor flow property and loose packing arrangement. The Fourier transform infrared (FT-IR) spectroscopic study revealed that the mucilage has characteristic peaks. From the study, it indicates that Feronia limonia mucilage powder has satisfactory pH and physicochemical properties, which can be used as pharmaceutical excipient in formulating various dosage forms.
Authors and Affiliations
Jyosna Doniparthi, Priyanjali H, Dhileep Ravilla , Blessy Sirigiri , Sireesha V, Anil Kumar Vepalapalli , Jeevana jyothi
Keywords
Related Articles
- EP ID EP164052
- DOI 10.7897/2230-8407.06798
- Views 97
- Downloads 0
PRELIMINARY PHYTOCHEMICAL SCREENING OF SEEDS OF PSORALEA CORYLIFOLIA
Psoralea corylifolia known as “Babchi” is a medicinal plant for the treatment of skin diseases. In India, indigenous herbal remedies such as Ayurveda and other Indian traditional medicines have since ancient times used p...
DIURETIC ACTIVITY OF PISTIA STRATIOTES LEAF EXTRACT IN RATS
The leaf extracts of Pistia stratiotes were subjected to screening of antidiabetic and diuretic activity in rats. The oral administration of the extracts (200mg/kg body weight) produced significant antihyperglycemic (P*&...
ENHANCING SOLUBILITY AND DISSOLUTION OF IBUPROFEN BY SPRAY DRYING USING PLURONIC F127
Ibuprofen, an anti-inflammatory drug, exhibits poor water solubility, dissolution and flow properties. Thus, the aim of the present study was to improve the solubility and dissolution rate of Ibuprofen by preparing micro...
IN VITRO FERTILIZATION
First written document dealing with infertility may be found in the Kahoun papyrus (oldest Egyptian medical text), dated to 2200-1950 BC. The early attribution of infertility to women persisted for centuries and was ofte...
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF AMLODIPINE BESYLATE AND ENALAPRIL MALEATE
Stability testing is a routine procedure performed on drug substances and drug products to provide evidence on how the quality of a drug varies with time under the influence of a variety of parameters. Environmental fact...