ISOLATION, SCREENING AND IDENTIFICATION OF CEFDINIR DEGRADING YEASTS FOR THE TREATMENT OF PHARMACEUTICAL WASTEWATER
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 8
Abstract
Objective: The aim of the present study was to isolate, screen and identify the cefdinir degrading yeasts for the treatment of pharmaceutical wastewater.Methods: The steps include isolation of yeasts from pharmaceutical wastewater, screening of yeasts for cefdinir degradation, studies on effects of pH, carbon and nitrogen sources on yeast growth, treatment of pharmaceutical wastewater using yeast.Results: Out of five yeast isolates, four were screened for cefdinir degradation and identified by molecular techniques. Yeast isolates were found to utilize cefdinir as sole carbon and energy source at an optimum pH 6.0. Addition of extra carbon and nitrogen sources in the growth medium did not show any improvement of yeast growth. Maximum cefdinir degradation by four yeast isolates was found to be 72%, 78%, 81% and 84% respectively and significant reduction in BOD, COD, TSS and TDS was noted after treating the pharmaceutical wastewater with the yeast isolates.Conclusion: The isolated yeasts may serve as potential remediation agents for the treatment of pharmaceutical wastewater containing cefdinir, a semi-synthetic cephalosporin derivative.Â
Authors and Affiliations
Adikesavan Selvi, Nilanjana Das
Keywords
Related Articles
- EP ID EP579733
- DOI -
- Views 61
- Downloads 0
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF IMPURITIES FROM OLMESARTAN MEDOXIMIL AND HYDROCHLOROTHIAZIDE TABLET
Objective: To develop and validate stability indicating RP-HPLC gradient method for simultaneous estimation of impurities and degradation products from Olmesartan Medoximil and Hydrochlorothiazide tablet.Methods: The chr...
EFFECT OF GARLIC (ALLIUM SATIVUM L) ON BIOCHEMICAL PARAMETERS AND HISTOPATHOLOGY OF PANCREAS OF ALLOXAN-INDUCED DIABETIC RATS
Objective: Garlic (Allium sativum. L) plays an important dietary role, as well as medicinal, for centuries. Even today the use of garlic is widespread and growing. The present study investigated the effect of garlic extr...
FORMULATION OF LEVOFLOXACIN AS ORODISPERSIBLE TABLETS USING A READY-MADE BLEND OF EXCIPIENTS COMPARED WITH CLASSIC FORMULATION STRATEGIES
Objective: Orodispersible tablets are designed to undergo rapid dispersal when they are placed in the mouth prior to being swallowed. The aim of this study was to compare the performance of a ready-made excipients blend...
IMPACT OF PROLONGED REDUCED-PRESSURE CONDITION PRIOR TO PRECURSOR LABELING ON THE LABELING EFFICIENCY OF F-18 FLUOROCHOLINE SYNTHESIS
Objective: The goal of this preliminary work was to observe the impact of the prolonged reduced-pressure condition prior to labeling stage on the F-18 Fluorocholine labeling yield at the end of synthesis.Methods: At this...
DEVELOPMENT AND VALIDATION OF A STABILITY INDICATING UPLC METHOD FOR THE ESTIMATION OF R-TELAPREVIR IN DRUG SUBSTANCE AND PHARMACEUTICAL DOSAGE FORM OF TELAPREVIR BY ENHANCED APPROACH
Objective: To develop a novel, simple, precise and stability indicating reverse phase ultra-performance liquid chromatographic (RP-UPLC) method and validate as per ICH guidelines for the quantification of R-Telaprevir in...