Juvenile Ankylosing Spondylitis (Literature Review and Own Findings)
Journal Title: Здоров`я дитини - Year 2016, Vol 4, Issue 72
Abstract
We present a review of current literature and findings of our own surveys of 35 children and 182 adults with ankylosing spondylitis. Compared with the disease in adults, juvenile ankylosing spondylitis has a number of clinical features, which occurs only in boys, manifests by a more frequent lesion of axial joints (shoulder, hip), development of systemic bone deficiency (osteopenia, osteoporosis), enthesitis (in particular, of the femoral condyles and the vertebral joints, but not achillodynia), uveitis, and cardiopathy, proliferation (and not destruction) of bone sections during the onset of spondylopathy and a rare involvement in the process of the lumbar spine and the formation of epiphyseal osteoporosis, higher blood concentrations of interleukin-8 and -17, but lower values of interleukin-1β, circulating immune complexes, fibrinogen, immunoglobulins А and G. It may be desirable to separate ankylosing spondylitis as a nosological form, such as juvenile idiopathic arthritis (in the recent past, juvenile rheumatoid arthritis).
Authors and Affiliations
O. Ye. Chernyshova, T. R. Polesova, Ye. D. Yehudina, O. V. Syniachenko
Keywords
Related Articles
- EP ID EP191999
- DOI -
- Views 99
- Downloads 0
Features of endocrine status in obese children and polymorphisms of the lactase gene
Background. Obesity is an imbalance of immunocytokine and neuroendocrine regulation of energy metabolism with excessive accumulation of adipose tissue in the body accompanied by the formation of a chronic proinflammatory...
The importance of correction of autonomic dysfunction in children with urinary disorders or How to improve the efficacy of neurogenic bladder therapy
The article presents a modern view on the problem of neurogenic bladder in children from the standpoint of awareness of the role of vegetative homeostasis. The importance of a differentiated approach to the correction of...
The Spectrum of Sensitization in Infants with IgE-Dependent Mechanism of Disease in a Large Industrial Area
Recently, the role of anthropogenic impact on the human bodysignificantly increased, which determines the spread of allergic pathologies in children. Among 318 infants with IgE-dependent skin diseases maximum level of hy...
Age features of the IgE-dependent food hypersensitivity in children of different ages diagnosed with prick- and patch-tests
Background. Food hypersensitivity (FH) is commonly diagnosed in children. Positive skin tests and elevated serum IgE levels indicate anaphylactic mechanisms of allergy symptoms, although in some cases they do not correla...
Issues of therapy for biliary pathology in children: the choice of the optimal solution
Background. Diseases of the hepatobiliary system are one of the most important problems of pediatric gastroenterology. Lesions of the biliary tract are associated with persistent changes in lipid metabolism that contrib...