Ketorolac vs. tramadol for pain management after abdominal surgery in children
Journal Title: Paediatrica Indonesiana - Year 2014, Vol 54, Issue 2
Abstract
Background Tramadol is a pure analgesic widely used forpostoperative treatment and well tolerated by children. Howevet;it has only a 50% efficacy. Ketorolac, a nonsteroid anriinflammation drug (NSAID), is widely used in adults and has upto 85% clinical efficacy. Data supporting the use of ketorolac inchildren has been limited.Objective To compare the clinical efficacies of intravenousketorolac and tramadol for moderatetosevere pain managementafter abdominal surgery in children.Methods A doubleblind controlled trial was conducted in Moh.Hoesin Hospital, Palembang, from January to June 2012. Subjectswere postoperative children aged 1 7 years who met the inclusioncriteria. T hey were randomized into two groups who receivedeither intravenous ketorolac or tramadol. Subjects assessedtheir pain level using the Face, Legs, Anns, Cry and Consolability(FLACC) pain scale. T he FLACC scores ::::;3 were considered toindicate clinical success of the intervention. Data were analyzedby Ttest, Chisquare test, and Fischer's exact test.Results Of the 60 subjects who underwent abdominal surgery withgeneral anesthesia, 31 (52%) were boys and 29 (48%) were girls.Subjects' mean age and body weight were 3.7 (SD 1.82) years and12.6 (SD 2.85) kg, respectively. Mean duration of surgery was 71.7(SD 21.11) minutes and mean postoperative FLACC score was6.6 (SD 0.5). Eight subjects dropped out of the study. Efficacies ofketorolac and tramadol were not significantly different at 21/26 and17/26, respectively (P=OJ5). In addition, there was no significantdifference in the number of patients experiencing a >3 FLACCscore decline between ketorolac and tramadol groups (P=0.61).Conclusion T here is no significant difference in the efficaciesof intravenous ketorolac and tramadol for moderatetoseverepain management after abdominal surgery in children. [PaediatrIndones.2014;54:118.21.].
Authors and Affiliations
Iman Hendarman, Silvia Triratna, Muhammad Kamaludin, Theodorus Theodorus
Keywords
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- EP ID EP458714
- DOI 10.14238/pi54.2.2014.118-21
- Views 91
- Downloads 0
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