Lipid Charecterization and Fatty Acid Profiles of Clarius batrachus and Its Defense Activity
Journal Title: Journal of Pharmaceutical Research International - Year 2015, Vol 7, Issue 5
Abstract
Innate Defense Components were being useful to identify and understand their mode of action on microbial pathogens. The present study portrays the qualitative and quantitative determination of endogenous lipids from the skin, intestine, kidney and liver of Clarius batrachus. The skin lipids were identified by TLC, which constitutes phosphatydyl serine (Ptd Ser) (48%), glycerophospholipids (23%), phosphoglyceride (20%), and 7% of cholesterol (C). The GC-MS FAME profile of the Skin comprised, the saturated fatty acid (SFA) with n-16 and n-18 as major fatty acids, 25.04% of palmitic (PAM) and 10.23% of stearic acid (STA). The fatty acid profiles and lipid classes of other organs were also identified and quantitated. The results from the present study bestowed to the skin lipid from the C.batrachus can be developed as a novel drug for multidrug resistant bacterial pathogens.
Authors and Affiliations
Giridharan Bupesh, Chinnaiah Amutha, Krishnan Saravana Murali, Natarajan Saran, Pitchaipillai Shanthi, Sakthivel Vasanth, E. Manikandan, Periasamy Subramanian
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