Lipid profile in pregnant women in South Eastern, Nigeria
Journal Title: International Journal of Medical and Health Sciences - Year 2015, Vol 4, Issue 3
Abstract
Lipid profile parameters viz: Total Cholesterol, Total Triglyceride, HDL-C, LDL-C and VLDL levels were determined in ninety apparently healthy pregnant women attending their routine antenatal clinic at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria. About 90 apparently healthy pregnant women were recruited into the study and their ages were between 18 and 40 years, they were grouped according to the following age groups viz: 18-24, 25-29,30-34 and ≥35 years of age and with 28,26,20 and 16 pregnant women respectively while another 30 apparently healthy non pregnant women were also included as control subjects. Women on contraceptives were excluded from the study. Total cholesterol, total triglyceride and HDL-C levels were determined using standard Chemical Pathology techniques. While LDL-C and VLDL-C parameters were derived from Total Cholesterol, Total triglyceride and HDL-C levels through calculations. It is puzzling to note the result of our research finding in the first, second and third trimesters showed that the levels of total cholesterol and total triglyceride in pregnant women were significantly higher than in non pregnant women at P<0.05. While the results HDL-C, LDL-C and VLDL follow the same trend. From the results obtained it is possible that these pregnant women could be predisposed to hyperlipidaemia during pregnancy, this could be attributed to their nutritional pattern. Our findings revealed that pregnant women in sub Saharan Africa may be more predisposed to hyperlipidaemia than non pregnant women.
Authors and Affiliations
Mbadugha, N. N. 1, Nnamah, N. K. 1, Mamah, V. O. , Onochie, A. U. , Ekwunoh, P. O. , Nwobodo, E. I, Ozuah, A. C, Ibegbu, V. O, Ebugosi, R. S.
Keywords
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