Liver Biopsy Study in Diseases of Paediatric Age Group
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
To determine pattern of liver disease in the paediatric age group. Materials and Methods: In the present study of 28 cases (including 5 postmortem biopsy), liver biopsy was done, out of which 24 cases could be diagnosed histologically .Slides were prepared from paraffin-embedded blocks, stained by routine H & E and special stains and were then reviewed. The frequency of each disorder, separately and in combination with the age group or gender of the patients was calculated and compared with other similar studies. Results: Incidence of liver involvement was slightly more (58.3%) in males. The most common age group which suffered from liver disease was 2-6 yrs (66.7%). The commonest cause of hepatomegaly was cirrhosis of liver (57.1%) followed by malnutrition (14.3%), chronic venous congestion (9.5%). Hyperbilirubinemia was present in 75% children of I.C.C., 50% children of post hepatitis cirrhosis and 25% of early cirrhosis. Overall it was seen in 46.7% children of cirrhosis.Liver biopsy is an essential diagnostic tool in various liver disorders, in that only in 62.6 % of our cases clinical diagnosis was consistent with histopatholgical changes. Liver biopsy is an essential diagnostic tool especially in cases of unknown hepatomegaly where diagnosis can only be done after histopathological study of liver tissue.
Authors and Affiliations
Dr Dileep Kumar Jain, Dr Malay Bajpai, Dr Vivek Gupta
Keywords
Related Articles
- EP ID EP591261
- DOI 10.9790/0853-1603011519
- Views 57
- Downloads 0
A Study on The Role of Septoplasty in Tubotympanic Diseases And Its Outcomes
Introduction: Chronic otitis media is classified as a tubotympanic disease and is characterized by central perforation. Eustachian tube is the principal focus in middle ear disease. Pathological findings in the nose or t...
An Atypical Presentation of HELLP Syndrome
Background: HELLP syndrome, named for 3 features of the disease (hemolysis, elevated liver enzyme levels, and low platelet levels), is a life-threatening condition that can potentially complicate pregnancyTypically occur...
Perinatal Mortality: An Observ Perinatal Mortality: An Observational Study At Tertiary Centre
Perinatal deaths are responsible for about 7% of the total global burden of disease. The present study was conducted in tertiary referral institute in Western Maharashtra, India, with a aim to study the frequency, classi...
Study of correlation between Robinson’s cytological grading and NBR histological grading of Breast carcinoma
Breast carcinoma is one of the most common cancers in women among the world. Early accurate diagnosis plays key role in treating patients. Cytological diagnosis and grading helps clinician to select appropriate treatment...
A Comparative Evaluation of Clinical And Radiological Scoring Systems in The Early Prediction of Severity in Acute Pancreatitis
Abstract : Acute pancreatitis is an acute inflammatory process involving pancreas and peri-pancreatic tissue, with a range of severity as well as various local and systemic complications. It is a common disorder causing...