LOCALIZED NEUROFIBROMA OF LABIUM MAJUS: A CASE REPORT
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 30
Abstract
Neurofibromatosis is an autosomal dominant progressive disorder with an incidence of approximately 1 in 3000 live births. Its recognized features include hyperpigmented skin lesions (Cafe-au-lait spots), neurofibromas, iris hamartomas, macrocephaly, central nervous system tumors, defects of the skull and facial bones, and vascular lesions. Involvement of the external genitalia is extremely unusual. 1,2 Neurofibromas of vulva are 5% of all benign vulval lesions, and about 18% of patients with von Recklinghausen’s disease have vulval neurofibromatosis as a component. 3 Although these tumours are usually small in size (Less than 3cm in diameter) and slow growing, giant rapidly growing solitary ones have been reported in the literature. 4 Neurofibromas involving the female genital tract commonly involve the clitoris and the labia but may also affect the vagina, cervix endometrium, myometrium, and ovary and may be associated with urinary tract neurofibromatosis. 3 Vulval neurofibromas have been associated with trauma such as episiotomies or other vulval injuries. 5
Authors and Affiliations
Bhavya S. Rao, Rama Raju H. E
Keywords
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- EP ID EP229133
- DOI 10.18410/jebmh/2015/631
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