Low Hemoglobin Levels in Infected Diabetic Foot Ulcer
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 1
Abstract
Background: Studies have shown that anemia is twice as common in diabetics compared with nondiabetics. Objective: We aimed to evaluate the prevalence of anemia in diabetic foot ulceration (DFU) patients and it’s correlation with infection. Methods: This study was conducted from October 2015 to the end of February 2016 and consisted of (55) Iraqi diabetic patients with foot ulcer that sub grouped to patients with non infected diabetic foot patients (n=25, group NIDFU), and patients with infected diabetic foot (n=30, group IDFU) according to erythrocyte sedimentation rate (ESR). Anthropometric indices and clinical examinations were done. Anemia is defined according to WHO as hemoglobin (Hb) levels <12 g/dL. Statistical analysis was done using t-test and Pearson correlation. Results: ESR of group NIDFU (25.2±14.26 mm/hr) was significantly lower (P = <0.001) in comparison to that of group IDFU (76.73±33.39 mm/hr).The mean values of Hb of NIDFU group (13.45±2.15 g/dl) was significantly higher (P = <0.001) than that of IDFU group (11.34±2.17 g/dl). In IDFU group; 63% were anemic while only 32% of NIDFU group have anemia. Pearson correlation of ESR in IDFU group revealed significant negative correlation with Hb (r= −0.386; P <0.05), while no significant correlation with Hb (r= 0.404; P >0.05) was found in NIDFU group. Conclusion: This prospective study showed a high incidence of anemia in patients with IDFU in contrast to NIDFU and a negative correlation was found between anemia and infection. Iron replacement and therapeutic strategies are recommended.
Authors and Affiliations
Isam Noori Salman, Shatha Abdul Wadood *2, Banan Akram Abualkasem3
Keywords
Related Articles
- EP ID EP388250
- DOI 10.9790/3008-1201040509
- Views 78
- Downloads 0
Phytochemical Compositions of Fruits of Three Musa Species at Three Stages of Development
This was designed to evaluates the phytochemical compositions of fruits of three Musa species at three stages of development. Spectrophotometric methods were used for the study. Results of the qualitative phytochemical a...
Gross Anatomical, Histological and Histochemical Studies of Thyroid Glands of African Giant Rat (Cricetomys gambianusWaterhouse, 1840)
The wild African giant rat is currently explored as a laboratory model for scientific research. The present study is aimed at investigating the gross morphology, histology and histochemistry of the thyroid gland of wild...
The impact of left ventricular thickness in hypertensive heart disease on right ventricular function: An Echocardiographic Strain Study
Background:In spite of heart remodeling such as left ventricular hypertrophy affects both left and right ventricles due to ventricular interdependence; still a few studies had examined the outcomes of these effects on ri...
Association between Elevated Serum Ferritin and HBA1C in Type 2 Diabetes Mellitus
Background and objectives : Diabetes is a disease of metabolic dysregulation. Recent studies have emphasized the role of serum ferritin in insulin resistance and the incidence of diabetes mellitus. However, the role of f...
Comparative Larvicidal and Residual Activity of Bacillus Thuringiensisvar. Israelensisand Temephos (1.0 % Sg) In Granules Against Culex Pipiens Pallens(Diptera: Culicidae) In Semi-Field Tests
The study looked at comparative larvicidal activity and residual effects of granular formulations of Bacillusthuringiensis var. Israelensis (Bti); a bio pesticide and temephos (Abate); phosphorus based nonsystemic pestic...