Lumbar Epidural Injections: Review of Efficacy and Discussion of Practice Options

Journal Title: Journal of Orthopedics & Rheumatology - Year 2015, Vol 2, Issue 1

Abstract

Background: In the United States, low back pain remains a common problem and a number one reason to see a physician in the outpatient setting. Etiology is complex and likely multifactorial and includes; degenerative disc disease, zygapophysial joint arthritis,vertebral misalignment, muscle strain, ligament sprain, myofascial pain, among others. Based on evidence of increased inflammatory response in disc herniation and degenerative discs, epidural steroid injections (ESI) have been used to treat lumbosacral radicular pain. Objective: To focus on the appropriate use of lumbar ESI in treating lumbosacral radicular pain in the United States, comparing and contrasting transforaminal, interlaminar, and caudal approaches for steroid delivery, as well as a comparison of commonly used steroid preparations. Methods: PubMED, MEDLINE, and OVID databases were reviewed utilizing the following subject headings: low back pain, epidural steroid injections, transforaminal epidural steroid injections (TFESI), interlaminar epidural steroid injections (ILESI), and caudal epidural steroid injections (CESI) dated from 2000 to 2014. The bibliographies of major articles and reviews were also cross-referenced for additional sources. Results: A number of articles that included randomized control trials, comprehensive and systematic reviews, and meta-analyses were found. These provided a broad, detailed overview of the subject, that we used to explore the data surrounding use of ESI for treatment of lumbosacral radicular pain. Conclusions: Most agree that the evidence for epidural steroid injection efficacy is strongest for short term relief of lumbosacral radicular pain. Most of the systemic reviews have agreed that the strongest evidence for TFESI use is for relief of unilateral lumbosacral radicular pain. The evidence suggests using ILESI in patients with bilateral and/ or multi-level lumbosacral radicular pain. The data correlates efficacy of CESI in low level bilateral or multilevel lumbosacral radicular pain as well as in patients with history of lumbar surgery.

Authors and Affiliations

Ashot S Kotcharian

Keywords

Related Articles

Searching for the Molecular Pathways Regulating Bone Mineral Density in the Proteome and RNA Interference Era

Osteoporosis is a polygenic disorder associated with low bone mineral density and deterioration of bone microarchitecture with increased chance of bone fractures. Although bone matrix mineralization and osteoporosis are...

A Systematic Review of Treatment Strategies for Lumbar Spine Fusion Surgery in Osteoporotic Patients

Purpose: Evaluate the current evidence in the literature on treatment strategies for lumbar spine fusion in patients with osteoporosis.Methods: A systematic review of the literature from 1950-2015. Results: The review o...

Musculoskeletal Hospital Admission and Surgical Procedure Rates among Patients Treated for Rheumatoid Arthritis in the Netherlands 1999-2012

Objectives: To assess trends in hospitalizations among patients receiving rheumatoid arthritis (RA)-treatment in a 14-year period compared with population references. Methods: Patients treated for RA with any disease-mo...

Noninvasive Measurements of Pressure for Detecting Compartment Syndromes

Background: We tested a noninvasive ultrasound, Pulse Phase Locked Loop (PPLL) technique for estimating Intramuscular Pressure (IMP) in a model Acute Compartment Syndrome (ACS); and compared it to a Near-Infrared Spectro...

Painful Patellar Partita Complicated with Intraarticular Ganglion

Painful patellar partita complicated with intraarticular ganglion cysts arising from the cruciate ligament is difficult to diagnose from the symptoms alone. In the patient reported here, knee pain was caused by patellar...

Download PDF file
  • EP ID EP208540
  • DOI 10.13188/2334-2846.1000015
  • Views 117
  • Downloads 0

How To Cite

Ashot S Kotcharian (2015). Lumbar Epidural Injections: Review of Efficacy and Discussion of Practice Options. Journal of Orthopedics & Rheumatology, 2(1), 1-12. https://europub.co.uk./articles/-A-208540